Dermatological Biopsies: The Role of Cryostats


In the ever-evolving landscape of medical technology, advancements continue to reshape the field of dermatology. One such groundbreaking innovation is the integration of cryostats in dermatological biopsies. Cryostats, originally developed for various histological applications, have found a niche in dermatology, offering enhanced precision and efficiency in skin biopsies. This article explores the significance of cryostats in dermatological procedures, shedding light on how this technology is transforming the landscape of skin diagnostics.

Understanding Cryostats:

A cryostat is a specialized piece of laboratory equipment designed for the preparation of thin tissue sections for microscopic examination. Unlike conventional methods that utilize paraffin embedding, cryostats operate at extremely low temperatures, allowing the rapid freezing of tissue specimens. This quick freezing process preserves cellular structures in their native state, providing dermatologists with a more accurate representation of the skin’s microarchitecture.

Benefits of Cryostats in Dermatological Biopsies:

  1. Rapid Processing: Cryostats enable dermatologists to process tissue samples rapidly. This is particularly crucial in dermatology, where timely results can be pivotal for patient management. The ability to freeze and section specimens quickly enhances the overall efficiency of the biopsy process.
  2. High-Quality Tissue Preservation: Traditional methods of tissue processing can lead to artifacts and alterations in cellular structures. Cryostats, by contrast, preserve tissues in a near-natural state. This is especially advantageous in dermatology, where accurate assessments of cellular morphology are essential for diagnosing conditions ranging from melanoma to inflammatory disorders.
  3. Real-Time Diagnostics: The speed at which cryostats operate allows for real-time diagnostics during surgical procedures such as Mohs surgery. Dermatologists can examine frozen sections immediately, guiding them in deciding the extent of excision required. This capability is particularly valuable in Mohs micrographic surgery, a precise technique often employed for skin cancer removal.
  4. Minimized Patient Discomfort: The swift processing time of cryostats translates into reduced wait times for patients undergoing biopsies. Minimizing the time between tissue removal and diagnostic assessment not only aids in faster treatment decisions but also contributes to a more comfortable experience for the patient.
  5. Enhanced Precision in Margin Assessment: Cryostats play a pivotal role in Mohs surgery by facilitating meticulous margin assessment. The rapid freezing and sectioning of tissue allow for precise evaluation of tumor margins, ensuring that cancerous cells are completely excised while minimizing the removal of healthy tissue.


The integration of cryostats into dermatological biopsies represents a significant stride towards precision medicine in the field of dermatology. The rapid processing, high-quality tissue preservation, real-time diagnostics, and enhanced precision in margin assessment are just a few of the benefits that this technology brings to the table. As the use of cryostats becomes more widespread, dermatologists can expect to see improved diagnostic accuracy and more streamlined procedures, ultimately leading to better outcomes for patients with skin conditions. The combination of technology and dermatology continues to pave the way for a new era of advanced diagnostics and patient care.

About MES

Since 2002, Medical Equipment Source has been providing laboratory equipment services to private practices and independent laboratories across the country and the world, empowering them to run more efficiently while providing better patient outcomes.

From laboratory setups to lab preventative maintenance to consulting contracts, Medical Equipment Source provides a comprehensive range of solutions to physicians and practice managers looking to grow their business by offering their own in-house lab services. Medical Equipment Source provides help with lab and exam room furnishings, consumables, repair services, lab equipment and layout, and more.

Today, Medical Equipment Source is an authority in the physician-owned lab market, with clients in 49 states and 30 countries. Those clients range from physicians who have launched their own labs to lab technicians who have built their own spaces as well as hospitals, universities and reference laboratories.

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